Short plays keep options alive
Two-letter plays can turn a blocked board into a scoring lane. They are especially useful when several small cross-words can be created in the same move.
WWF has its own dictionary
Do not assume every Scrabble word is accepted in Words With Friends, or vice versa. Check unfamiliar candidates against the current in-app dictionary.
Use premium squares deliberately
A tiny word can score well when a valuable tile reaches a premium square. Compare several placements before using a blank or a flexible S.